Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model

<p>Abstract</p> <p>Background</p> <p>The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a distinct subset of peptides and the enormous number of possible peptid...

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Bibliographic Details
Main Authors: Mittelmann Hans D, Bordner Andrew J
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/41