The effect of Amine modification on siRNA delivery of redox-responsive PEGylated amphiphilic micellar nanoparticles for triple negative breast cancer therapy

We developed a set of methoxypoly (ethyleneglycol)-co-poly(N3-ε-caprolactone) (mPEG-N3PCL)copolymers with different types of amine linkers and investigated the contribution of the introduced amino linker to the gene delivery efficiency of nanoparticles. The nanoparticles were crosslinked from the ca...

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Bibliographic Details
Main Authors: Fatemeh Mehradnia, Cameron Alexander
Format: Article
Language:English
Published: University of Huddersfield Press 2022-11-01
Series:British Journal of Pharmacy
Subjects:
Online Access:https://www.bjpharm.org.uk/article/id/1119/