LDHA: The Obstacle to T cell responses against tumor

LDHA: The Obstacle to T cell responses against tumor

Immunotherapy has become a successful therapeutic strategy in certain solid tumors and hematological malignancies. However, this efficacy of immunotherapy is impeded by limited success rates. Cellular metabolic reprogramming determines the functionality and viability in both cancer cells and immune...

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Bibliographic Details
Main Authors: Yu Tang, Shuangshuang Gu, Liqun Zhu, Yujiao Wu, Wei Zhang, Chuanxiang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
LDHA
lactate
T cell responses
tumor
metabolic reprogramming
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1036477/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1036477/full

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