LDHA: The Obstacle to T cell responses against tumor
Immunotherapy has become a successful therapeutic strategy in certain solid tumors and hematological malignancies. However, this efficacy of immunotherapy is impeded by limited success rates. Cellular metabolic reprogramming determines the functionality and viability in both cancer cells and immune...
Main Authors: | Yu Tang, Shuangshuang Gu, Liqun Zhu, Yujiao Wu, Wei Zhang, Chuanxiang Zhao |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-11-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1036477/full |
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