ATAD2 is a driver and a therapeutic target in ovarian cancer that functions by upregulating CENPE

Abstract Ovarian cancer is a complex disease associated with multiple genetic and epigenetic alterations. The emergence of treatment resistance in most patients causes ovarian cancer to become incurable, and novel therapies remain necessary. We identified epigenetic regulator ATPase family AAA domai...

Full description

Bibliographic Details
Main Authors: Praveen Guruvaiah, Suresh Chava, Chiao-Wang Sun, Nirupama Singh, Courtney A. Penn, Romi Gupta
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05993-9