Endothelin-A Receptor Antagonist Alleviates Allergic Airway Inflammation via the Inhibition of ILC2 Function

Endothelin-A Receptor Antagonist Alleviates Allergic Airway Inflammation via the Inhibition of ILC2 Function

Allergic airway inflammation is a universal airway disease that is driven by hyperresponsiveness to inhaled allergens. Group 2 innate lymphoid cells (ILC2s) produce copious amounts of type 2 cytokines, which lead to allergic airway inflammation. Here, we discovered that both peripheral blood of huma...

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Bibliographic Details
Main Authors: Xiaogang Zhang, Ziyang Chen, Shaowen Zuo, Hengbiao Sun, Xinyao Li, Xiao Lu, Zhe Xing, Meiqi Chen, Jingping Liu, Gang Xiao, Yumei He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
endothelin-A receptor antagonist
BQ123
therapeutic
allergic airway inflammation
group 2 innate lymphoid cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.835953/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.835953/full

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