Inhibitory Effects of Ketamine on Lipopolysaccharide-Induced Microglial Activation
Microglia activated in response to brain injury release neurotoxic factors including nitric oxide (NO) and proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Ketamine, an anesthetic induction agent, is generally reserved for use in patients with severe hyp...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2009-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2009/705379 |