Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction

Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction

BackgroundDiscoveries in the identification of transcription factors, growth factors and extracellular signaling molecules have led to the detection of downstream targets that modulate valvular tissue organization that occurs during development, aging, or disease. Among these, matricellular protein,...

Full description

Bibliographic Details
Main Authors: Suniti Misra, Shibnath Ghatak, Ricardo A. Moreno-Rodriguez, Russell A. Norris, Vincent C. Hascall, Roger R. Markwald
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
periostin
α5β1-integrin
valve interstitial cushion cells
Fak
Pak1
Cdc42
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.649862/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.649862/full

Similar Items