Inhibition of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase enzyme by dipeptides identified in dry-cured ham

Abstract High cholesterolemia is a key risk factor for the development of cardiovascular diseases, which are the main cause of mortality in developed countries. Most therapies are focused on the modulation of its biosynthesis through 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoAR) inhibit...

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Bibliographic Details
Main Authors: Alejandro Heres, Leticia Mora, Fidel Toldrá
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Food Production, Processing and Nutrition
Subjects:
Online Access:https://doi.org/10.1186/s43014-021-00058-w