Reversal learning and associative memory impairments in a BACHD rat model for Huntington disease.

Chorea and psychiatric symptoms are hallmarks of Huntington disease (HD), a neurodegenerative disorder, genetically characterized by the presence of expanded CAG repeats (>35) in the Huntingtin (HTT) gene. HD patients present psychiatric symptoms prior to the onset of motor symptoms and we recent...

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Bibliographic Details
Main Authors: Yah-Se K Abada, Huu Phuc Nguyen, Bart Ellenbroek, Rudy Schreiber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3815226?pdf=render