Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes

Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes

ABSTRACT West Nile virus (WNV) is an emerging neuroinvasive flavivirus that now causes significant morbidity and mortality worldwide. The innate and adaptive immune responses to WNV infection have been well studied in C57BL/6J inbred mice, but this model lacks the variations in susceptibility, immun...

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Bibliographic Details
Main Authors: Jessica B. Graham, Sunil Thomas, Jessica Swarts, Aimee A. McMillan, Martin T. Ferris, Mehul S. Suthar, Piper M. Treuting, Renee Ireton, Michael Gale, Jennifer M. Lund
Format: Article
Language:English
Published: American Society for Microbiology 2015-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00493-15

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https://journals.asm.org/doi/10.1128/mBio.00493-15

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