Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis.
Evidence from human genetic studies of several disorders suggests that interactions between alleles at multiple genes play an important role in influencing phenotypic expression. Analytical methods for identifying Mendelian disease genes are not appropriate when applied to common multigenic diseases...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-03-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2653647?pdf=render |