Modulation of GABAB receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks

Modulation of GABAB receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks

BackgroundStimulation of gamma-aminobutyric acid (GABA) activity through GABA receptor agonists is the basic mechanism of many anticonvulsant drugs. Nevertheless, many of these GABergic drugs have adverse cognitive effects. We previously found that GABAB receptors (GABABRs) in the insula regulate op...

Full description

Bibliographic Details
Main Authors: Nan Wu, Tao Sun, Xin Wu, Hongguang Chen, Zhen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
GABABR
insula
Intellicage
epilepsy
operant associative memory
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1042227/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1042227/full

Similar Items