Impact of the RTS,S malaria vaccine candidate on naturally acquired antibody responses to multiple asexual blood stage antigens.

Impact of the RTS,S malaria vaccine candidate on naturally acquired antibody responses to multiple asexual blood stage antigens.

Partial protective efficacy lasting up to 43 months after vaccination with the RTS,S malaria vaccine has been reported in one cohort (C1) of a Phase IIb trial in Mozambique, but waning efficacy was observed in a smaller contemporaneous cohort (C2). We hypothesized that low dose exposure to asexual s...

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Bibliographic Details
Main Authors: Joseph J Campo, Carlota Dobaño, Jahit Sacarlal, Caterina Guinovart, Alfredo Mayor, Evelina Angov, Sheetij Dutta, Chetan Chitnis, Eusebio Macete, John J Aponte, Pedro L Alonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3192128?pdf=render

Internet

http://europepmc.org/articles/PMC3192128?pdf=render

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