Potential of Gold Nanoparticles in Current Radiotherapy Using a Co-Culture Model of Cancer Cells and Cancer Associated Fibroblasts

Potential of Gold Nanoparticles in Current Radiotherapy Using a Co-Culture Model of Cancer Cells and Cancer Associated Fibroblasts

Many cancer therapeutics are tested in vitro using only tumour cells. However, the tumour promoting effect of cancer associated fibroblasts (CAFs) within the tumour microenvironment (TME) is thought to reduce cancer therapeutics’ efficacy. We have chosen pancreatic ductal adenocarcinoma (PDAC) as ou...

Full description

Bibliographic Details
Main Authors: Abdulaziz Alhussan, Nicholas Palmerley, Julian Smazynski, Joanna Karasinska, Daniel J. Renouf, David F. Schaeffer, Wayne Beckham, Abraham S. Alexander, Devika B. Chithrani
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
MIA PaCa-2
cancer associated fibroblasts
co-culture
monoculture
gold nanoparticle
pancreatic cancer
Online Access:https://www.mdpi.com/2072-6694/14/15/3586

Internet

https://www.mdpi.com/2072-6694/14/15/3586

Similar Items