Combining immunoprofiling with machine learning to assess the effects of adjuvant formulation on human vaccine-induced immunity

Adjuvants produce complex, but often subtle, effects on vaccine-induced immune responses that, nonetheless, play a critical role in vaccine efficacy. In-depth profiling of vaccine-induced cytokine, cellular, and antibody responses (“immunoprofiling”) combined with machine-learning holds the promise...

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Bibliographic Details
Main Authors: Sidhartha Chaudhury, Elizabeth H. Duncan, Tanmaya Atre, Sheetij Dutta, Michele D. Spring, Wolfgang W. Leitner, Elke S. Bergmann-Leitner
Format: Article
Language:English
Published: Taylor & Francis Group 2020-02-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2019.1654807