Visual and digital assessment of Ki-67 in breast cancer tissue - a comparison of methods

Abstract Background In breast cancer (BC) Ki-67 cut-off levels, counting methods and inter- and intraobserver variation are still unresolved. To reduce inter-laboratory differences, it has been proposed that cut-off levels for Ki-67 should be determined based on the in-house median of 500 counted tu...

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Bibliographic Details
Main Authors: Anette H. Skjervold, Henrik Sahlin Pettersen, Marit Valla, Signe Opdahl, Anna M. Bofin
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Diagnostic Pathology
Subjects:
Online Access:https://doi.org/10.1186/s13000-022-01225-4