Manipulation of cell:cell contacts and mesoderm suppressing activity direct lineage choice from pluripotent primitive ectoderm-like cells in culture.

Manipulation of cell:cell contacts and mesoderm suppressing activity direct lineage choice from pluripotent primitive ectoderm-like cells in culture.

In the mammal, the pluripotent cells of embryo differentiate and commit to either the mesoderm/endoderm lineages or the ectoderm lineage during gastrulation. In culture, the ability to direct lineage choice from pluripotent cells into the mesoderm/endoderm or ectoderm lineages will enable the develo...

Full description

Bibliographic Details
Main Authors: James N Hughes, Jennifer M Washington, Zhiqiang Zheng, Xiuwen K Lau, Charlotte Yap, Peter D Rathjen, Joy Rathjen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2679147?pdf=render

Internet

http://europepmc.org/articles/PMC2679147?pdf=render

Similar Items