Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts

Effects of Endochondral and Intramembranous Ossification Pathways on Bone Tissue Formation and Vascularization in Human Tissue-Engineered Grafts

Bone grafts can be engineered by differentiating human mesenchymal stromal cells (MSCs) via the endochondral and intramembranous ossification pathways. We evaluated the effects of each pathway on the properties of engineered bone grafts and their capacity to drive bone regeneration. Bone-marrow-deri...

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Bibliographic Details
Main Authors: Jonathan C. Bernhard, Darja Marolt Presen, Ming Li, Xavier Monforte, James Ferguson, Gabriele Leinfellner, Patrick Heimel, Susanna L. Betti, Sharon Shu, Andreas H. Teuschl-Woller, Stefan Tangl, Heinz Redl, Gordana Vunjak-Novakovic
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
endochondral
intramembranous
ossification
bone tissue engineering
mesenchymal stromal cells
Online Access:https://www.mdpi.com/2073-4409/11/19/3070

Internet

https://www.mdpi.com/2073-4409/11/19/3070

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