Potential Role of Flavivirus NS2B-NS3 Proteases in Viral Pathogenesis and Anti-flavivirus Drug Discovery Employing Animal Cells and Models: A Review

Potential Role of Flavivirus NS2B-NS3 Proteases in Viral Pathogenesis and Anti-flavivirus Drug Discovery Employing Animal Cells and Models: A Review

Flaviviruses are known to cause a variety of diseases in humans in different parts of the world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore new drug targets must be explored. The flavivirus NS2B-NS3 proteases are responsible for the cleavage of the fla...

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Bibliographic Details
Main Authors: Abdul Wahaab, Bahar E Mustafa, Muddassar Hameed, Nigel J. Stevenson, Muhammad Naveed Anwar, Ke Liu, Jianchao Wei, Yafeng Qiu, Zhiyong Ma
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
flaviviruses
NS2B-NS3 proteases
genome organization
pathogenesis
characterization
antiviral drug target
Online Access:https://www.mdpi.com/1999-4915/14/1/44

Internet

https://www.mdpi.com/1999-4915/14/1/44

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