Tumor-associated macrophages: an accomplice in solid tumor progression

Abstract In many solid tumor types, tumor-associated macrophages (TAMs) are important components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly associated with poor survival in solid tumor patients. In this review, we describe the origins of TAMs and their polarization...

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Bibliographic Details
Main Authors: Yibing Chen, Yucen Song, Wei Du, Longlong Gong, Haocai Chang, Zhengzhi Zou
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-019-0568-z