12-Deacetyl-12-epi-Scalaradial, a Scalarane Sesterterpenoid from a Marine Sponge Hippospongia sp., Induces HeLa Cells Apoptosis via MAPK/ERK Pathway and Modulates Nuclear Receptor Nur77

12-Deacetyl-12-epi-Scalaradial, a Scalarane Sesterterpenoid from a Marine Sponge Hippospongia sp., Induces HeLa Cells Apoptosis via MAPK/ERK Pathway and Modulates Nuclear Receptor Nur77

12-Deacetyl-12-<i>epi</i>-scalaradial, a scalarane sesterterpenoid from a marine sponge <i>Hippospongia sp</i>, has been reported to possess cytotoxic activity on HepG2, MCF-7, and HCT-116 cells. However, there is no research to indicate that 12-deacetyl-12-<i>epi</i...

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Bibliographic Details
Main Authors: Mi Zhou, Bo-Rong Peng, Wenjing Tian, Jui-Hsin Su, Guanghui Wang, Ting Lin, Dequan Zeng, Jyh-Horng Sheu, Haifeng Chen
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Marine Drugs
Subjects:
12-deacetyl-12-<i>epi</i>-scalaradial
HeLa cells
apoptosis
Nur77
MAPK/ERK pathway
Online Access:https://www.mdpi.com/1660-3397/18/7/375

Internet

https://www.mdpi.com/1660-3397/18/7/375

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