Anti-diabetic drugs, insulin and metformin, have no direct interaction with hepatitis C virus infection or anti-viral interferon response

Anti-diabetic drugs, insulin and metformin, have no direct interaction with hepatitis C virus infection or anti-viral interferon response

Hepatitis C virus (HCV) infection is associated with insulin resistance (IR) and type 2 diabetes (T2D). Chronic HCV patients with IR and T2D appear to have a decreased response to the standard pegylated-interferon-alpha and ribavirin (PEG-IFN/RBV) anti-viral therapy. Insulin and metformin are anti-d...

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Bibliographic Details
Main Authors: Mohamad S. Hakim, Xinying Zhou, Yijin Wang, Maikel P. Peppelenbosch, Qiuwei Pan
Format: Article
Language:English
Published: AIMS Press 2014-01-01
Series:AIMS Molecular Science
Subjects:
HCV infection
insulin
metformin
interferon
Online Access:http://www.aimspress.com/article/10.3934/molsci.2014.1.49/fulltext.html

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http://www.aimspress.com/article/10.3934/molsci.2014.1.49/fulltext.html

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