Solid bioneedle-delivered influenza vaccines are highly thermostable and induce both humoral and cellular immune responses.

The potential of bioneedles to deliver influenza vaccines was investigated. Four influenza vaccine formulations were screened to determine the optimal formulation for use with bioneedles. The stability of the formulations after freeze-drying was checked to predict the stability of the influenza vacc...

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Bibliographic Details
Main Authors: Peter C Soema, Geert-Jan Willems, Klaas van Twillert, Gijsbert van de Wijdeven, Claire J Boog, Gideon F A Kersten, Jean-Pierre Amorij
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3966824?pdf=render