Embryonic development of selectively vulnerable neurons in Parkinson’s disease

Abstract A specific set of brainstem nuclei are susceptible to degeneration in Parkinson’s disease. We hypothesise that neuronal vulnerability reflects shared phenotypic characteristics that confer selective vulnerability to degeneration. Neuronal phenotypic specification is mainly the cumulative re...

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Bibliographic Details
Main Authors: Miguel A. P. Oliveira, Rudi Balling, Marten P. Smidt, Ronan M. T. Fleming
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-017-0022-4