Rubus chingii Hu. unripe fruits extract ameliorates carbon tetrachloride-induced liver fibrosis and improves the associated gut microbiota imbalance

Rubus chingii Hu. unripe fruits extract ameliorates carbon tetrachloride-induced liver fibrosis and improves the associated gut microbiota imbalance

Abstract Background The unripe fruits of Rubus chingii Hu. (“Fu-peng-zi” in Chinese) is a well-known herbal tonic in traditional Chinese medicine (TCM) for tonifying liver and kidney. However, little is known regarding its therapeutic efficacy against liver fibrosis and the underlying mechanism. Met...

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Bibliographic Details
Main Authors: Jianjun Wu, Dingqi Zhang, Bo Zhu, Siqi Wang, Yongbin Xu, Congcong Zhang, Hailing Yang, Shunchun Wang, Ping Liu, Luping Qin, Wei Liu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Chinese Medicine
Subjects:
Rubus chingii Hu.
Liver fibrosis
Hepatic stellate cells
TGF-β/Smads
Gut microbiota
Online Access:https://doi.org/10.1186/s13020-022-00607-6

Internet

https://doi.org/10.1186/s13020-022-00607-6

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