Bacterial Tyrosinase Inhibition, Hemolytic and Thrombolytic Screening, and In Silico Modeling of Rationally Designed Tosyl Piperazine-Engrafted Dithiocarbamate Derivatives

Bacterial Tyrosinase Inhibition, Hemolytic and Thrombolytic Screening, and In Silico Modeling of Rationally Designed Tosyl Piperazine-Engrafted Dithiocarbamate Derivatives

Piperazine is a privileged moiety that is a structural part of many clinical drugs. Piperazine-based scaffolds have attracted the attention of pharmaceutical and medicinal scientists to develop novel, efficient therapeutic agents owing to their significant and promising biological profile. In the cu...

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Bibliographic Details
Main Authors: Ameer Fawad Zahoor, Freeha Hafeez, Asim Mansha, Shagufta Kamal, Muhammad Naveed Anjum, Zohaib Raza, Samreen Gul Khan, Jamila Javid, Ali Irfan, Mashooq Ahmad Bhat
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomedicines
Subjects:
Tosyl piperazine
dithiocarbamate derivatives
ultrasonic-assisted green synthesis
bacterial tyrosinase inhibition
hemolytic activity
thrombolytic
Online Access:https://www.mdpi.com/2227-9059/11/10/2739

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https://www.mdpi.com/2227-9059/11/10/2739

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