HIV Infection Drives Foam Cell Formation via NLRP3 Inflammasome Activation

HIV Infection Drives Foam Cell Formation via NLRP3 Inflammasome Activation

Persistent immune activation is linked to an increased risk of cardiovascular disease (CVD) in people with HIV (PWH) on antiretroviral therapy (ART). The NLRP3 inflammasome may contribute to elevated CVD risk in PWH. This study utilized peripheral blood mononuclear cells (PBMCs) from 25 PWH and 25 H...

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Bibliographic Details
Main Authors: Maurizio Caocci, Meng Niu, Howard S. Fox, Tricia H. Burdo
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
HIV
oxLDL
foam cells
NLRP3 inflammasome
cardiovascular disease
PWH
Online Access:https://www.mdpi.com/1422-0067/25/4/2367

Internet

https://www.mdpi.com/1422-0067/25/4/2367

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