Phloretin Targets Polyphosphate Kinase 1 to Attenuate Acinetobacter baumannii Virulence and Persistence In Vitro and In Vivo

Phloretin Targets Polyphosphate Kinase 1 to Attenuate Acinetobacter baumannii Virulence and Persistence In Vitro and In Vivo

Acinetobacter baumannii (A. baumannii) is well known for its virulence and persistence, particularly in intensive care units. Therefore, new strategies and candidates to treat A. baumannii infection are urgently needed considering the emergence of drug-resistant bacteria. Polyphosphate kinase 1 (PPK...

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Bibliographic Details
Main Authors: Hongfa Lv, Shufang Li, Jian Guan, Peng Zhang, Lingcong Kong, Hongxia Ma, Dan Li, Xuming Deng, Xiaodi Niu, Jianfeng Wang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Engineering
Subjects:
Acinetobacter baumannii
Virulence
Persistence
Phloretin
Polyphosphate kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S2095809924005605

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http://www.sciencedirect.com/science/article/pii/S2095809924005605

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