Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility

ABSTRACT Living organisms are constantly exposed to DNA damage stress caused by endogenous and exogenous events. Eukaryotic cells have evolutionarily conserved DNA damage checkpoint surveillance systems. We previously reported that a unique transcription factor, Bdr1, whose expression is strongly in...

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Bibliographic Details
Main Authors: Kwang-Woo Jung, Yeonseon Lee, Eun Young Huh, Soo Chan Lee, Sangyong Lim, Yong-Sun Bahn
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01726-18