The Biogenesis and Functions of piRNAs in Human Diseases

Piwi-interacting RNAs (piRNAs) are a novel type of small noncoding RNAs, which are 26–30 nt in length and bind to Piwi proteins. These short RNAs were originally discovered in germline cells and are considered as key regulators for germline maintenance. A growing body of evidence has now extended ou...

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Bibliographic Details
Main Authors: Xi Wu, Yutian Pan, Yuan Fang, Jingxin Zhang, Mengyan Xie, Fengming Yang, Tao Yu, Pei Ma, Wei Li, Yongqian Shu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301499