Copper (I)-Chloroquine Complexes: Interactions with DNA and Ferriprotoporphyrin, Inhibition of β-Hematin Formation and Relation to Antimalarial Activity

A new Cu(I)-chloroquine (CQ) complex [Cu(CQ)(PPh<sub>3</sub>)<sub>2</sub>]NO<sub>3</sub> (<b>1</b>) was synthesized and characterized, and its mechanism of action studied concomitant with the previously reported complex [Cu(CQ)<sub>2</sub>]...

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Bibliographic Details
Main Authors: Wilmer Villarreal, William Castro, Sorenlis González, Marylin Madamet, Rémy Amalvict, Bruno Pradines, Maribel Navarro
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/8/921