Copper (I)-Chloroquine Complexes: Interactions with DNA and Ferriprotoporphyrin, Inhibition of β-Hematin Formation and Relation to Antimalarial Activity

A new Cu(I)-chloroquine (CQ) complex [Cu(CQ)(PPh<sub>3</sub>)<sub>2</sub>]NO<sub>3</sub> (<b>1</b>) was synthesized and characterized, and its mechanism of action studied concomitant with the previously reported complex [Cu(CQ)<sub>2</sub>]...

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書誌詳細
主要な著者: Wilmer Villarreal, William Castro, Sorenlis González, Marylin Madamet, Rémy Amalvict, Bruno Pradines, Maribel Navarro
フォーマット: 論文
言語:English
出版事項: MDPI AG 2022-07-01
シリーズ:Pharmaceuticals
主題:
オンライン・アクセス:https://www.mdpi.com/1424-8247/15/8/921