Copper (I)-Chloroquine Complexes: Interactions with DNA and Ferriprotoporphyrin, Inhibition of β-Hematin Formation and Relation to Antimalarial Activity
A new Cu(I)-chloroquine (CQ) complex [Cu(CQ)(PPh<sub>3</sub>)<sub>2</sub>]NO<sub>3</sub> (<b>1</b>) was synthesized and characterized, and its mechanism of action studied concomitant with the previously reported complex [Cu(CQ)<sub>2</sub>]...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-07-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/15/8/921 |