Application of an iPSC‐Derived Organoid Model for Localized Scleroderma Therapy

Application of an iPSC‐Derived Organoid Model for Localized Scleroderma Therapy

Abstract Localized scleroderma (LoS) is a rare chronic disease with extensive tissue fibrosis, inflammatory infiltration, microvascular alterations, and epidermal appendage lesions. However, a deeper understanding of the pathogenesis and treatment strategies of LoS is currently limited. In the prese...

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Bibliographic Details
Main Authors: Jie Ma, Wei Li, Ruiyuan Cao, Dunqin Gao, Qiyu Zhang, Xiao Li, Biyou Li, Luye Lv, Mansheng Li, Junyi Jiang, Yujie Wang, Jun Li, Zhihong Wu, Yunping Zhu, Wu Zhong, Shuyang Zhang, Ling Leng
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Advanced Science
Subjects:
epithelial and mesenchymal organoid
human induced pluripotent stem cells
localized scleroderma
proteomics
skin
Online Access:https://doi.org/10.1002/advs.202106075

Internet

https://doi.org/10.1002/advs.202106075

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