ROS-Induced DCTPP1 Upregulation Contributes to Cisplatin Resistance in Ovarian Cancer

ROS-Induced DCTPP1 Upregulation Contributes to Cisplatin Resistance in Ovarian Cancer

Cisplatin resistance hinders the improvement of the prognosis of patients with ovarian cancer. Cisplatin induces cancer cell apoptosis by inducing reactive oxygen species (ROS). dCTP pyrophosphatase 1 (DCTPP1) is a newly discovered dNTP pyrophosphatase. This study aimed to identify the role of DCTPP...

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Bibliographic Details
Main Authors: Yu Wang, Peishi Chen, Xueping Chen, Daoyuan Gong, Yingsong Wu, Liping Huang, Yao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
ovarian cancer
DCTPP1
cisplatin
ROS
cisplatin resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.838006/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.838006/full

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