On Characterizing the Interactions between Proteins and Guanine Quadruplex Structures of Nucleic Acids
Guanine quadruplexes (G4s) are four-stranded secondary structures of nucleic acids which are stabilized by noncanonical hydrogen bonding systems between the nitrogenous bases as well as extensive base stacking, or pi-pi, interactions. Formation of these structures in either genomic DNA or cellular R...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
|
Series: | Journal of Nucleic Acids |
Online Access: | http://dx.doi.org/10.1155/2017/9675348 |