Single‐cell quantification of IL‐2 response by effector and regulatory T cells reveals critical plasticity in immune response
Understanding how the immune system decides between tolerance and activation by antigens requires addressing cytokine regulation as a highly dynamic process. We quantified the dynamics of interleukin‐2 (IL‐2) signaling in a population of T cells during an immune response by combining in silico model...
Main Authors: | Ofer Feinerman, Garrit Jentsch, Karen E Tkach, Jesse W Coward, Matthew M Hathorn, Michael W Sneddon, Thierry Emonet, Kendall A Smith, Grégoire Altan‐Bonnet |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2010-01-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2010.90 |
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