HIF-1α siRNA Leads to Apoptosis of Pancreatic Cancer Cells under Hypoxic Conditions

HIF-1α siRNA Leads to Apoptosis of Pancreatic Cancer Cells under Hypoxic Conditions

OBJECTIVE To explore the role of hypoxic inducible factor-1α (HIF-1 α ) in the proliferation and apoptosis of pancreatic cancer cells under hypoxic conditions. METHODS A cassette encoding small interference RNA (siRNA) targeting HIF-1 α mediated by recombinant adeno-associated virus (rAAV) was co...

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Bibliographic Details
Main Author:	Chuangui CHEN, Jianqiu CHEN, Jinjin SUN
Format:	Article
Language:	English
Published:	China Anti-Cancer Association 2009-02-01
Series:	Cancer Biology & Medicine
Subjects:	recombinant adeno-associated virus (rAAV) hypoxia inducible factor (HIF) small interference RNA (siRNA) proliferation apoptosis.
Online Access:	http://www.cancerbiomed.org/index.php/cocr/article/view/167

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