In silico approaches in carcinogenicity hazard assessment: case study of pregabalin, a nongenotoxic mouse carcinogen

In silico approaches in carcinogenicity hazard assessment: case study of pregabalin, a nongenotoxic mouse carcinogen

In silico toxicology protocols are meant to support computationally-based assessments using principles that ensure that results can be generated, recorded, communicated, archived, and then evaluated in a uniform, consistent, and reproducible manner. We investigated the availability of in silico mode...

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Bibliographic Details
Main Authors: Douglas A. Keller, Arianna Bassan, Alexander Amberg, Leigh Ann Burns Naas, Jon Chambers, Kevin Cross, Frances Hall, Gloria D. Jahnke, Amarjit Luniwal, Serena Manganelli, Jordi Mestres, Amy L. Mihalchik-Burhans, David Woolley, Raymond R. Tice
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Toxicology
Subjects:
In silico toxicology protocol
mode of action
pregabalin
non-genotoxic carcinogen
oxidative stress
chronic inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2023.1234498/full

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https://www.frontiersin.org/articles/10.3389/ftox.2023.1234498/full

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