Radiation and chemotherapy for high‐risk lower grade gliomas: Choosing between temozolomide and PCV

Abstract Purpose The majority of patients with high‐risk lower grade gliomas (LGG) are treated with single‐agent temozolomide (TMZ) and radiotherapy despite three randomized trials showing a striking overall survival benefit with adjuvant procarbazine, lomustine, and vincristine (PCV) chemotherapy a...

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Bibliographic Details
Main Authors: Susan G. R. McDuff, Jorg Dietrich, Katelyn M. Atkins, Kevin S. Oh, Jay S. Loeffler, Helen A. Shih
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.2686