Associations between DNA methylation and gene regulation depend on chromatin accessibility during transgenerational plasticity

Abstract Background Epigenetic processes are proposed to be a mechanism regulating gene expression during phenotypic plasticity. However, environmentally induced changes in DNA methylation exhibit little-to-no association with differential gene expression in metazoans at a transcriptome-wide level....

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Bibliographic Details
Main Authors: Samuel N. Bogan, Marie E. Strader, Gretchen E. Hofmann
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-023-01645-8