Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer

Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases, characterized by a treatment-resistant and invasive nature. In line with these inherent aggressive characteristics, only a subset of patients shows a clinical response to the standard of care therapies, thereby high...

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Bibliographic Details
Main Authors: Maxim Le Compte, Edgar Cardenas De La Hoz, Sofía Peeters, Felicia Rodrigues Fortes, Christophe Hermans, Andreas Domen, Evelien Smits, Filip Lardon, Timon Vandamme, Abraham Lin, Steve Vanlanduit, Geert Roeyen, Steven Van Laere, Hans Prenen, Marc Peeters, Christophe Deben
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00480-y

Internet

https://doi.org/10.1038/s41698-023-00480-y

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