GRHL2-controlled gene expression networks in luminal breast cancer

Abstract Grainyhead like 2 (GRHL2) is an essential transcription factor for development and function of epithelial tissues. It has dual roles in cancer by supporting tumor growth while suppressing epithelial to mesenchymal transitions (EMT). GRHL2 cooperates with androgen and estrogen receptors (ER)...

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Bibliographic Details
Main Authors: Zi Wang, Bircan Coban, Haoyu Wu, Jihed Chouaref, Lucia Daxinger, Michelle T. Paulsen, Mats Ljungman, Marcel Smid, John W. M. Martens, Erik H. J. Danen
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-022-01029-5