Pre-existing humoral immunity to low pathogenic human coronaviruses exhibits limited cross-reactive antibodies response against SARS-CoV-2 in children

Pre-existing humoral immunity to low pathogenic human coronaviruses exhibits limited cross-reactive antibodies response against SARS-CoV-2 in children

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes asymptomatic or mild symptoms, even rare hospitalization in children. A major concern is whether the pre-existing antibodies induced by low pathogenic human coronaviruses (LPH-CoVs) in children can cross-react with SARS-Co...

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Bibliographic Details
Main Authors: Nina Li, XueYun Li, Jiani Wu, Shengze Zhang, Lin Zhu, Qiqi Chen, Ying Fan, Zhengyu Wu, Sidian Xie, Qi Chen, Ning Wang, Nan Wu, Chuming Luo, Yuelong Shu, Huanle Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
low pathogenic human coronaviruses
SARS-CoV-2
cross-reactive antibody
neutralizing activity
antigen specific antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1042406/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1042406/full

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