Single-cell transcriptomics of human-skin-equivalent organoids

Summary: Several methods for generating human-skin-equivalent (HSE) organoid cultures are in use to study skin biology; however, few studies thoroughly characterize these systems. To fill this gap, we use single-cell transcriptomics to compare in vitro HSEs, xenograft HSEs, and in vivo epidermis. By...

Full description

Bibliographic Details
Main Authors: Adam R. Stabell, Grace E. Lee, Yunlong Jia, Kirsten N. Wong, Shuxiong Wang, Ji Ling, Sandrine D. Nguyen, George L. Sen, Qing Nie, Scott X. Atwood
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005223