Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury

Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury

Cerebrovascular dysfunction resulting from traumatic brain injury (TBI) significantly contributes to poor patient outcomes. Recent studies revealed the involvement of iron metabolism in neuronal survival, yet its effect on vasculature remains unclear. This study aims to explore the impact of endothe...

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Bibliographic Details
Main Authors: Yidan Liang, Yanglingxi Wang, Chao Sun, Yi Xiang, Yongbing Deng
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Brain Research Bulletin
Subjects:
Traumatic brain injury (TBI)
Cerebrovascular function
Brain microvascular endothelial cells (BMECs)
Ferroptosis
Cerebral blood flow (CBF)
Online Access:http://www.sciencedirect.com/science/article/pii/S036192302400011X

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http://www.sciencedirect.com/science/article/pii/S036192302400011X

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