New frontiers in the medical management of gastrointestinal stromal tumours

The tyrosine kinase inhibitor (TKI) imatinib has radically changed the natural history of KIT-driven gastrointestinal stromal tumours (GISTs). Approved second-line and third-line medical therapies are represented by the TKIs sunitinib and regorafenib, respectively. While imatinib remains the cardina...

Full description

Bibliographic Details
Main Authors: Alessandro Mazzocca, Andrea Napolitano, Marianna Silletta, Mariella Spalato Ceruso, Daniele Santini, Giuseppe Tonini, Bruno Vincenzi
Format: Article
Language:English
Published: SAGE Publishing 2019-05-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835919841946