Pressure Loading Induces DNA Damage in Human Hepatocyte Line L02 Cells via the ERK1/2–Dicer Signaling Pathway

Pressure Loading Induces DNA Damage in Human Hepatocyte Line L02 Cells via the ERK1/2–Dicer Signaling Pathway

Alteration of liver tissue mechanical microenvironment is proven to be a key factor for causing hepatocyte injury and even triggering the occurrence of hepatocellular carcinoma; however, the underlying mechanisms involved are not fully understood. In this study, using a customized, pressure-loading...

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Bibliographic Details
Main Authors: Yanping Tang, Yanan Fan, Qing Luo, Guanbin Song
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
compressive stress
hepatocyte
DNA damage
ERK1/2–Dicer signal
Online Access:https://www.mdpi.com/1422-0067/23/10/5342

Internet

https://www.mdpi.com/1422-0067/23/10/5342

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