VALIDATION METHOD FOR DETERMINATION OF THE SULFUR HEXAFLUORIDE IN PLASMA SAMPLES OF EXPERIMENTAL ANIMALS

A new GCMS-based method for quantitative determination of active substance of new contrast drug based on sulfur hexafluoride (SH) in the rat blood plasma is produced. A ratio plot of peak area of sulfur hexafluoride to peak area of internal standard toluene [y, S(SH)/S(toluene)] versus concentration...

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Bibliographic Details
Main Authors: S. S. Vlasov, S. V. Krivoshchekov, M. K. Zamanova, M. V. Belousov, A. M. Guriev, M. S. Yusubov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/171