Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer’s Disease

Previous systems-based proteomic approaches have characterized alterations in protein co-expression networks of unfractionated asymptomatic (AsymAD) and symptomatic Alzheimer’s disease (AD) brains. However, it remains unclear how sample fractionation and sub-proteomic analysis influences the organiz...

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Bibliographic Details
Main Authors: Lenora Higginbotham, Eric B. Dammer, Duc M. Duong, Erica Modeste, Thomas J. Montine, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/7/3/30