Investigation of Tumor Heterogeneity Using Integrated Single-Cell RNA Sequence Analysis to Focus on Genes Related to Breast Cancer-, EMT-, CSC-, and Metastasis-Related Markers in Patients with HER2-Positive Breast Cancer

Investigation of Tumor Heterogeneity Using Integrated Single-Cell RNA Sequence Analysis to Focus on Genes Related to Breast Cancer-, EMT-, CSC-, and Metastasis-Related Markers in Patients with HER2-Positive Breast Cancer

Human epidermal growth factor receptor 2 (HER2) protein, which is characterized by the amplification of <i>ERBB2</i>, is a molecular target for HER2-overexpressing breast cancer. Many targeted HER2 strategies have been well developed thus far. Furthermore, intratumoral heterogeneity in H...

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Bibliographic Details
Main Authors: Sho Shiino, Momoko Tokura, Jun Nakayama, Masayuki Yoshida, Akihiko Suto, Yusuke Yamamoto
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
breast cancer
human epidermal growth factor receptor 2
heterogeneity
Online Access:https://www.mdpi.com/2073-4409/12/18/2286

Internet

https://www.mdpi.com/2073-4409/12/18/2286

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